In SDX Interest Rates you can change the settings of the various profiles (and indeed which profile is in use) in the Settings window (see Customizing SDX Interest Rates).
There are a number of ways of accessing the Settings window, depending on which page you are currently in.
In:
A pricing page in the ribbon bar in the Home tab click the Settings button. This opens the Settings window in the Default Settings tab > General tab.
A market data page, e.g., the Volatility Surface page or the Yield Curve page, you access the Settings window via the Settings button at the top of the page. This action opens the Settings window in the relevant tab for the page from which you accessed it.
Once you have accessed the Settings window by default you see the customization settings for the active profile.
If you want to see and/or edit the customization settings for a different profile, you do this via the View Profile Settings dropdown list.